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NFL Week 2 picks and predictions

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Steelers Bengals Football

Pittsburgh cornerback Ahkello Witherspoon (25) and the Steelers host the New England Patriots on Sunday in Week 2 of the NFL season.

The Thursday night showdown between the Los Angeles Chargers at the Kansas City Chiefs highlights the Week 2 NFL slate, as FrontPageBets GM/Content Director Mike Szvetitz makes his picks and predictions.

Coming out of the opening week of the NFL season, there were a lot of questions to be answered.

Which teams are for real? Which teams are all hype? Which teams were underrated? Which teams will finish the way they started?

Week 2 should give us a better idea of what's what in the NFL in 2022, as one game does not a season make.

We do know one thing, however, the Los Angeles Chargers and the Kansas City Chiefs are legit; and if Thursday night's Chiefs' win showed us anything, the AFC West will be fun to watch this year. 

As the second Sunday of the season approaches, FrontPageBets takes a look at each of game's betting line and picks.

We finished Week 1, 8-8 against the spread and 9-7 straight up.

NFL Week 2 picks and predictions

(All odds courtesy of DraftKings and are subject to change)

Sunday, Sept. 18

New York Jets vs. Cleveland Browns

  • When: 1 p.m., CBS
  • Spread: Browns -6.5 (-110); Jets +6.5 (-110)
  • Money line: Browns -265; Jets +225
  • Over/Under: 39.5 (-110)
  • The pick: Browns, 24-10

 Washington Commanders vs. Detroit Lions

  • When: 1 p.m., FOX
  • Spread: Lions -1.5 (-110); Commanders +1.5 (-110)
  • Money line: Lions -125; Commanders +105
  • Over/Under: 48.5 (-110)
  • The pick: Commanders, 31-26

Tampa Bay Buccaneers vs. New Orleans Saints

  • When: 1 p.m., FOX
  • Spread: Buccaneers -2.5 (-115); Saints +2.5 (-105)
  • Money line: Buccaneers -140; Saints +120
  • Over/Under: 44 (-110)
  • The pick: Buccaneers, 33-30

Carolina Panthers vs. New York Giants

  • When: 1 p.m., FOX
  • Spread: Giants -2 (-110); Panthers +2 (-110)
  • Money line: Giants -130; Panthers +110
  • Over/Under: 43.5 (-110)
  • The pick: Giants, 21-17

New England Patriots vs. Pittsburgh Steelers

  • When: 1 p.m., CBS
  • Spread: Patriots -2 (-110); Steelers +2 (-110)
  • Money line: Patriots -130; Steelers +110
  • Over/Under: 40 (-110)
  • The pick: Steelers, 21-20

Indianapolis Colts vs. Jacksonville Jaguars

  • When: 1 p.m., CBS
  • Spread: Colts -4 (-110); Jaguars +4 (-110)
  • Money line: Colts -195; Jaguars +165
  • Over/Under: 45.5 (-110)
  • The pick: Colts, 27-20

Miami Dolphins vs. Baltimore Ravens

  • When: 1 p.m., CBS
  • Spread: Ravens -3.5 (-110); Dolphins +3.5 (-110)
  • Money line: Ravens -180; Dolphins +155
  • Over/Under: 44.5 (-110)
  • The pick: Ravens, 25-21

Atlanta Falcons vs. Los Angeles Rams

  • When: 4:05 p.m., FOX
  • Spread: Rams -10.5 (-110); Falcons +10.5 (-110)
  • Money line: Rams -520; Falcons +410
  • Over/Under: 46.5 (-110)
  • The pick: Rams, 28-20

Seattle Seahawks vs. San Francisco 49ers

  • When: 4:05 p.m., FOX
  • Spread: 49ers -8.5 (-110); Seahawks +8.5 (-110)
  • Money line: 49ers -390; Seahawks +320
  • Over/Under: 41 (-110)
  • The pick: Seattle, 22-20

In this week's FPBcast, Gerry Ahern and Mike Szvetitz mull over their picks and predictions for the week that was and will be in football.

Cincinnati Bengals vs. Dallas Cowboys

  • When: 4:25 p.m., CBS
  • Spread: Bengals -7 (-115); Cowboys +7 (-105)
  • Money line: Bengals -315; Cowboys +260
  • Over/Under: 41.5 (-110)
  • The pick: Bengals, 28-10

Houston Texans vs. Denver Broncos

  • When: 4:25 p.m., CBS
  • Spread:  Broncos -10 (-110); Texans +10 (-110)
  • Money line: Broncos -490; Texans +390
  • Over/Under: 45 (-110)
  • The pick: Broncos, 21-17

Arizona Cardinals vs. Las Vegas Raiders

  • When: 4:25 p.m., CBS
  • Spread: Raiders -5.5 (-110); Cardinals +5.5 (-110)
  • Money line: Raiders -240; Cardinals +200
  • Over/Under: 51.5 (-110)
  • The pick: Raiders, 30-28

Chicago Bears vs. Green Bay Packers

  • When: 8:20 p.m., NBC
  • Spread: Packers -10 (-110); Bears +10 (-110)
  • Money line: Packers -450; Bears +360
  • Over/Under: 41.5 (-110)
  • The pick: Packers, 20-15

Monday, Sept. 19

Tennessee Titans vs. Buffalo Bills

  • When: 7:15 p.m., ESPN
  • Spread: Bills -10 (-110); Titans +10 (-110)
  • Money line: Bills -460; Titans +370
  • Over/Under: 48 (-110)
  • The pick: Bills, 30-21

Minnesota Vikings vs. Philadelphia Eagles

  • When: 8:30 p.m., ABC
  • Spread: Eagles -2 (-110); Vikings +2 (-110)
  • Money line: Eagles -130; Vikings +110
  • Over/Under: 50.5 (-110)
  • The pick: Vikings, 28-23

Gambling problem? There is help. Call 1-800-522-4700 or visit the National Council on Problem Gambling for help.

Mike Szvetitz is the General Manager and Content Director for FrontPageBets.com. Szvetitz is a 22-year veteran reporter and editor, including serving 17 years as a sports editor in Florida, Alabama and Virginia, covering everything from preps to pros. His "View From The Lazy Boy" column won multiple state and national awards. He can be reached at mszvetitz@timesdispatch.com.

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